Pluspunten
In the technical/scientific side, the intelligence and friendliness of most of the co-workers. Hiring for good personality (lack of aggressive arrogance) and high ability. Willingness to help and share. Few egotistical mainpulators I've come in contact with on my side. Science + tech types who get their job done well.
Minpunten
Internal computer support for scientific needs is woefully underdeveloped (hardware and software) far worse than even basic academic labs, much less a Yahoo or Google. Essentially they have no clue and no distinction between some random app-server and hard-core scientific cluster simulation. Continuous downscaling about what IT will support or offer or install, enforced centralization, and of course totally forbidding science or devel to administer their own systems & software installation (i.e. be root). See "advice to senior management".